If a hard-to-heal wound is not treated, then chances are that over time, it will get bigger and deeper. This significantly increases the chances of infection, which if severe enough, may require hospitalization. If the tissue damage from infection is extensive, surgery or even amputation may be needed. To prevent this complication, your provider may use cutting edge technology like artificial skin therapy, hyperbaric oxygen and other advanced therapies to promote rapid wound healing. And when your wound is healed, your life can go back to normal.